Mesothelioma is caused by prolonged exposure to asbestos. Most cases occur in those working in direct contact, but it can be acquired indirectly by the asbestos that workers bring into their homes or by living near a manufacturer.
Pleural: Most common symptom, pleural effusion, occurs when mesothelial cells in the visceral and parietal pleura overproduce fluid. This may lead to shortness of breath, pain/difficulty breathing and a persistent cough. Less often, fever, weight-loss and/or night sweats. Patients may have no symptoms or just a feeling of malaise or being unwell.
Peritoneal: Accumulated peritoneal fluid causes abdominal swelling, pain with nausea and weight-loss, and possibly a palpable mass. Less commonly is anemia, pedal edema, bowel obstruction and/or abnormal clotting.
Pericardial: Symptoms can be very similar to pleural mesothelioma and other maladies of the heart and/or lungs, but may also include exertion-induced chest pain, palpitations, and face and upper-extremity swelling.