What Tests Are Used To Diagnose Mesothelioma?

Chest x-ray

  • A chest x-ray can reveal a pleural effusion when more than 300 mL of fluid is present in the pleural cavity.
  • Other signs of pleural mesothelioma that can be seen on a chest x-ray include pleural calcifications, thickening of the pleural, or an irregular pleural-based mass.

CT and MRI

  • They are used to determine the tumor burden, demonstrate pleural thickening, assess enlargement of lymph nodes, and to identify effusions.

Tests of tissue and fluid samples

  • Thorancetesis is used to obtain pleural fluid, if an effusion is present.
  • Thoracoscopy can be used to sample a pleural or pericardial tumor.
  • Laproscopy is used to see and obtain a biopsy of a peritoneal tumor.
  • Mediastinoscopy allows for biopsy and visualization of the lymph nodes.

Electron microscopy

  • The distinction between malignant mesothelioma and benign inflammatory conditions may be difficult. Electron microscopy can be confirmatory.

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